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| 2/15/2010 - Reprogenetics is proud to offer array CGH to detect all 24 chromosome aneuploidies. The test has NO CANCELLATION FEE, can be ordered on the day of the biopsy without pretesting of parents, has a very low 2% rate of embryos undiagnosed, and a very low error rate. Preliminary clinical data on a population of average 38 years of age showed that the technique reduced miscarriages to a mere 7%. | Read |
| 1/20/2010 – Reprogenetics has determined that couples undergoing PGD for gender selection overwhelmingly do so for the purpose of family balancing, with an equal preference for both genders (Colls et al. 2009b). | Read |
1/5/2010 - We have proven that although microarray technology can detect all aneuploidies in embryos, the simpler and cheaper FISH test, if modified, can detect up 90% of them. | Read |
1/3/2010 - Reprogenetics has a manuscript in press (Fischer et al. 2010) showing that patients with translocations and recurrent pregnancy loss benefit from PGD by increasing their odds at keeping their pregnancies to term. | Read |
| 1/1/2010 - Reprogenetics clinical results with comparative Genome hybridization are now in press. This technique allows for the analysis of all chromosome aneuploidies. | Read |
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| PGD BREAKING NEWS |
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6/29/2010 (a)– At the annual meeting of European Society Human Reproduction and Embryology (ESHRE) in Rome, The ESHRE taskforce on PGD presented encouraging results on the use of PGD when using array CGH for testing human eggs by polar body analysis. | Read |
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6/29/2010 (b)– At the same ESHRE meeting in Rome, Reprogenetics presented results on using array CGH for the testing all numerical chromosome abnormalities in embryos. It reported a very low error rate and encouraging pregnancy outcomes. The error rate presented by Reprogenetics was lower than that reported by the ESHRE taskforce (see previous news). | Read |
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6/28/2010 – At the annual meeting of European Society Human Reproduction and Embryology (ESHRE) in Rome, The Director of Reprogenetics UK and Oxford University Professor Dagan Wells was honored with a Merck Serono Grant for Fertility Innovation (GFI), entitled “Rapid inexpensive DNA fragmentation analysis of sperm & cumulus cells” | Read |
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| 5/1/2010 - Reprogenetics is proud to announce and welcome Gary Harton as its new Manager of Molecular Genetics. | Read More |
| 4/15/2010 - Reprogenetics and PracticeHwy.com, Inc. Announce Partnership to Offer a PGD Portal for eIVF. | Read More |
| Previous ones - | Read |
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| PGD DIAGNOSIS |
| Reprogenetics provides PGD analysis to IVF centers, including PGD of aneuploidy for advanced maternal age (such as Down syndrome), repeated IVF failure, recurrent spontaneous abortions, chromosome translocations and inversions, as well as PGD for gene defects such as Cystic fibrosis, fragile X, Myotonic Dystrophy, Thalasaemia, Tay Sachs, and others. We also provide embryologist that can perform embryo biopsy and cell processing. |
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| GENETIC COUNSELING FOR PATIENTS |
| Patients interested in PGD services could contact an IVF center for which we provide services or directly contact our genetic counselor for an in depth discussion of your case. |
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ASSOCIATIONS
www.IVFonline.com
www.LifeGlobal.com
www.ivflabs.com
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MORE STORIES |
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Reprogenetics obtains a license to perform PGD in NY state for any type of PGD
Dear Colleague: In July of 2003, laboratories and assisted reproductive technology (ART) providers were notified that a New York State laboratory permit would be required for facilities performing preimplantation genetic diagnosis (PGD) on single cells derived from embryos by molecular genetic and/or cytogenetic techniques. | Read |
10.15.2007 - Empire Genomics and Reprogenetics join forces to improve Preimplantation Genetic Diagnosis (PGD)
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07. 05.2007 - World leading PGD experts are issuing a rebuttal to an article on preimplantation genetic diagnosis (PGD)
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07.15, 2007 - A report by Colls et al. of Reprogenetics shows a significant reduction of spontaneous abortions and an increase in pregnancies reaching term after using PGD with "no Result rescue"
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| Microarray technology to assess gene expression profiles of human oocytes and embryos. Introduction: The current knowledge of molecular mechanisms during early development is pretty rudimentary. | Read |
Results of PGD for infertility in 3597 cycles
Introduction: Preimplantation genetic Diagnosis of aneuploidy, has been offered clinically since 1993, but it is not until the last few years that through the use of reference PGD laboratories, the technique is available to all USA-based IVFcenters. | Read |
Maternal age is the most important parameter predicting aneuploidy yet it is an unpredictable indicator of chromosome abnormalities
Introduction: The increase of aneuploidy with maternal age has been demonstrated both with live birth, fetus, embryos and oocyte data. | Read |
The importance of a full chromosome count in PGD
PGD-AS using FISH is limited by the number of chromosomes that can be analysed. | Read |
Full Karyotype Interphase Cells Analysis
Early human development depends on the correct temporal and spatial expression of thousands of genes. | Read |
Restrictive art laws and PGD
Introduction: It is an irony that in some countries such as Germany and Italy multiple pregnancy and embryo cryopreservation have been artificially diminished by restrictive laws limiting the number of eggs inseminated. | Read |
Preimplantation genetic diagnosis (PGD) for chromosome structural aberrations: Outcome and comparison
Introduction: Since 1995, Reprogenetics has performed over 4,500 PGD cycles. | Read |
Embryonic chromosome abnormalities
The presence of numerical chromosome abnormalities in human embryos was studied using fluorescence in situ hybridization with up to 9 chromosome specific probes. |Read |
2/2006 High rates of chromosome abnormalities are found in embryos from egg donors, suggesting that PGD may be recommended in egg donor cycles.
Embryo chromosome studies show high rates of abnormalities, above 50%, but most embryos studied before this study were from patients 35 and older. | Read |
1/2006: PGD significantly reduces the risk of pregnancy loss after IVF
The incidence of miscarriage is correlated with maternal age. The majority of the miscarriages are chromosomally abnormal. | Read |
Reprogenetics demonstrates that patients with recurrent pregnancy loss can benefit from PGD
The objective of the study was to determine if Preimplantation Genetic Diagnosis (PGD) and transfer of chromosomally normal embryos would decrease spontaneous abortion rates in patients suffering from recurrent pregnancy loss (RPL). | Read |
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